Unchained Labs HUNK Protein Stability Analyzer Formulation Optimization system, very clean, appears to have light use, decommissioned from Merck.
Technical Specs:- Minimum protein concentration per ΔG: 25 μg/mL IgG (protein dependent)
- Typical volume required per ΔG: 1 mL
- Time to measure each ΔG: Average 1 hour
- Experiment temperature operating range: Constant 2°C above ambient to 30°C (±2°C)
- Automatic formulations preparation: Up to 12 formulations for each of 8 series, total of 96 conditions
- Protein stock temperature: 4°C to ambient
- Fluorescence detection: 150 W Xe lamp
- Fluorescence excitation and emission range: 190–890 nm ex, 200–900 nm em photomultiplier
- Fluorescence detection dynamic range: Five orders of magnitude
- Environmental conditions: Temperature range: 18–28°C
- Physical dimensions: 56 cm W x 71 cm D x 87 cm H, 91 kg
- Electrical: Auto switching power supply, voltage 100–240 V AC, 50–60 Hz
- Safety standards: CE
This is a $200,000 machine new from Unchained Labs.
User guide included. Also we have a contact at Unchained Labs to connect you with to get this registered to your company.
Add some muscle to your formulation testing process. The HUNK makes the hard stuff easy. It measures ΔGs for biologics and formulations using chemical denaturation, and does it totally hands-off.
In a nutshell, the HUNK measures a time-tested thermodynamic value, ΔG, using chemical denaturation.
Formulate on the fly. Compare biologics stability. Size up protein aggregation. Find out if your protein aggregates before or after denaturation. Pump it all out on day 1 with the HUNK, and know right away if you need to switch up your routine.
